1-CHLORO-3,5-BIS[O-(4-TOLUOYL)]-2-DEOXYRIBOSE
3,5-Di-O-p-toluyl-2-deoxy-a-D-ribofuranosyl chloride
CAS: 4330-21-6
Molecular Formula: C21H21ClO5
1-CHLORO-3,5-BIS[O-(4-TOLUOYL)]-2-DEOXYRIBOSE - Names and Identifiers
1-CHLORO-3,5-BIS[O-(4-TOLUOYL)]-2-DEOXYRIBOSE - Physico-chemical Properties
| Molecular Formula | C21H21ClO5 |
| Molar Mass | 388.84 |
| Density | 1.28 |
| Melting Point | 117-119 °C |
| Boling Point | 518.4±50.0 °C(Predicted) |
| Flash Point | 185.6°C |
| Solubility | Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly, Sonicated), Methanol |
| Vapor Presure | 7.5E-11mmHg at 25°C |
| Appearance | Solid |
| Color | Off-White to Light Grey |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Stability | Moisture Sensitive |
| Refractive Index | 1.583 |
| MDL | MFCD00079148 |
| Use | NSC 148837 is used as a precursor for the synthesis of unnatural β-D-ribofuranosyl containing nucleosides and nucleotides. |
1-CHLORO-3,5-BIS[O-(4-TOLUOYL)]-2-DEOXYRIBOSE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29321900 |
1-CHLORO-3,5-BIS[O-(4-TOLUOYL)]-2-DEOXYRIBOSE - Introduction
3, chloride is an organic compound. Its chemical formula is C24H23ClO4 and its molecular weight is 402.89. The following is a description of the properties, uses, preparation and safety information of the compound:
properties: 3, chloride is white to light yellow solid. It is relatively stable at room temperature and soluble in some organic solvents, such as methanol, dimethylformamide, etc.
Purpose: The compound is often used as an important reagent in organic synthesis. It can be used to synthesize organic compounds such as nucleotides, nucleotide esters, and oligonucleotide sequences. It plays an important role in biochemical research and in the pharmaceutical industry.
preparation method: 3, chloride can be obtained by reacting p-toluoyl chloride with 2-deoxy-D-ribofuranose. Generally, the two are reacted in an appropriate organic solvent, a base catalyst is added, and after a series of steps and treatments, the target product can be obtained.
Safety information: 3. chloride is an organic compound, so appropriate safety measures need to be taken when handling and using. It is irritating, direct contact with skin and eyes should be avoided, and protective gloves and glasses should be worn if necessary. In addition, you should avoid inhaling its dust or vapor, because it may be irritating to the respiratory tract.
properties: 3, chloride is white to light yellow solid. It is relatively stable at room temperature and soluble in some organic solvents, such as methanol, dimethylformamide, etc.
Purpose: The compound is often used as an important reagent in organic synthesis. It can be used to synthesize organic compounds such as nucleotides, nucleotide esters, and oligonucleotide sequences. It plays an important role in biochemical research and in the pharmaceutical industry.
preparation method: 3, chloride can be obtained by reacting p-toluoyl chloride with 2-deoxy-D-ribofuranose. Generally, the two are reacted in an appropriate organic solvent, a base catalyst is added, and after a series of steps and treatments, the target product can be obtained.
Safety information: 3. chloride is an organic compound, so appropriate safety measures need to be taken when handling and using. It is irritating, direct contact with skin and eyes should be avoided, and protective gloves and glasses should be worn if necessary. In addition, you should avoid inhaling its dust or vapor, because it may be irritating to the respiratory tract.
Last Update：2024-04-10 22:29:15
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